Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and β1-integrin-dependent mechanism
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چکیده
منابع مشابه
Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanism.
Branching morphogenesis is a fundamental process in the development of the kidney. This process gives rise to a network of ducts, which form the collecting system. Defective branching can lead to a multitude of kidney disorders including agenesis and reduced nephron number. The formation of branching tubules involves changes in cell shape, cell motility, and reorganization of the cytoskeleton. ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2010
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00543.2009